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5.4. Pentylenetetrazol (PTZ) induced seizures
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Mice between 1 and 2 months old were injected intraperitoneally with PTZ at a dose of 30 mg/kg and were observed for 30 min. Latencies to myoclonic and GTCS were recorded. The susceptibility to PTZ-induced seizures was assessed by survival cure. Mantel-Cox method was used for statistics. The experimenter was blind to the genotypes.
Copyright and License information: ©2021
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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