3.3. Determination of Experimental logP Values

GG Gábor Girst
Sándor B. Ötvös
FF Ferenc Fülöp
GB György T. Balogh
AH Attila Hunyadi
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Lipophilicity measurements of hydrocurcumins were performed by dissolving the compounds in the organic solvents (octanol and toluene) at 1mg/mL concentration and mixing them with water (1:5 and 1:10 ratios, each in five replicates). After 24 h the concentration of the compounds in the aqueous phase were calculated by using a calibration dilution series measured on RP-HPLC system. The concentration of the organic phase was calculated from the concentration of the aqueous phase.

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