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FinnGen

TL Triin Laisk
ML Maarja Lepamets
MK Mariann Koel
EA Erik Abner
RM Reedik Mägi
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FinnGen is a public–private partnership project combining data from Finnish biobanks and electronic health records from different registries. After a 1-year embargo, the FinnGen summary stats are available for download. In this study, we used the results from the FinnGen release R3, which includes data from 135,638 individuals and more than 1800 disease endpoints. FinnGen individuals have been genotyped with Illumina and Affymetrix arrays and imputed to the population-specific SISu v3 importation reference panel. Genetic association testing has been carried out with SAIGE12. The FinnGen disease endpoint “Vitamin B12 deficiency anemia” included all individuals with the ICD10 D51 diagnosis as cases. FinnGen summary statistics included prefiltered variants (minimum allele count >5 and imputation INFO score >0.6). For more information on genotype data, disease endpoints and GWAS analyses, please see https://finngen.gitbook.io/documentation/.

Copyright and License information: The Author(s) ©2021
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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