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Radiosynthesis of [18F]DPA-714 was performed on a Trasis AllinOne (AIO) module (Ans, Belgium). The synthesiser is equipped with 36 rotary actuators (arranged in two rows) to which a dedicated disposable cassette can be attached. The cassette for [18F]DPA-714 productions was assembled in-house, starting from a commercially available Trasis [18F]FDOPA cassette, as described in “Cassette preparation” section.
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