Participants

Participants were enrolled in longitudinal studies on aging and dementia conducted at the Washington University Knight Alzheimer’s Disease Research Center and in a longitudinal driving study (R01AG056466). All participants were cognitively normal as determined by a score of 0 on the Clinical Dementia Rating (CDR®), were 65 years old or older, had a valid driver’s license, drove at least once per week, and had in vivo CSF collection and/or amyloid imaging. The study protocol was approved by the Washington University Human Research Protection Office, and written informed consent was obtained.