2.1. Patients

Twenty-five consecutive patients with intermediate and high-risk PCa, planned for laparoscopic radical prostatectomy at Umeå University Hospital, were included. Ethical approval was granted (Dnr 2016-229-31M) by the Regional Ethics Board and the Radiation Protection Committee at Umeå University Hospital. All patients signed informed consent to participate in the study. Inclusion criteria were histologically confirmed intermediate or high-risk PCa planned to be treated with radical prostatectomy, ≥2 months since the last prostate biopsy, Gleason score 3 + 4 or higher, written informed consent, and age >18 years. Exclusion criteria were contraindication to PET or MRI (non-MRI-safe implants, claustrophobia, physical limitations e.g., back pain), neoadjuvant/concomitant androgen deprivation therapy (medical or surgical castration; anti-androgens), TUR-P performed within 6 months, metastatic disease, and creatinine clearance <30 ml/min.