Statement of ethical approval and registration

The study was conducted in accordance with the principles of Declaration of Helsinki and Ethical Guidelines for Medical and Health Research Involving Human Subjects and was approved by the ethics committee of the Japan Conference of Clinical Research. Written informed consent was obtained from all participants. This study was conducted by a principal investigator of Tokyo Center Clinic. This study was registered on October 01, 2018 in the database of the University Hospital Medical Information Network before enrolling the participants (Registration No. UMIN000034347).