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2.1. Drug targeted genes (DTG) collection

XL Xuan Li
HS Hefen Sun
QL Qiqi Liu
YL Yang Liu
YH Yifeng Hou
WJ Wei Jin
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The 3D structures of doxorubicin, epirubicin, and taxane were downloaded from PubChem (https://pubchem.ncbi.nlm.nih.gov/), and drug‐targeted genes (DTGs) and proteins were obtained from PharmMapper and ranked by calculating the PharmMapper fit score of the drug ligands using the drug's structure. 20 , 21 Homo sapiens genes with fit scores higher than 0.4 were considered DTGs.

Copyright and License information:  ©2021 The Authors. published by John Wiley & Sons Ltd.
This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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