Gene Ontology analysis

NB Nasim Biglari
IG Isabella Gaziano
JS Jonas Schumacher
JR Jan Radermacher
LP Lars Paeger
PK Paul Klemm
WC Weiyi Chen
SC Svenja Corneliussen
CW Claudia M. Wunderlich
MS Michael Sue
SV Stefan Vollmar
TK Tim Klöckener
TS Tamara Sotelo-Hitschfeld
AA Amin Abbasloo
FE Frank Edenhofer
FR Frank Reimann
FG Fiona M. Gribble
HF Henning Fenselau
PK Peter Kloppenburg
FW Frank T. Wunderlich
JB Jens C. Brüning
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The regulated GO48 terms were derived using the clusterProfiler R package49 and visualized by mapping the percentage of regulated genes to the total GO term gene count against significant gene counts and adjusted P values per term. We visualized the GO term as a heat map, where each row represents a differentially expressed gene belonging to the term and each column represents a sample. To ensure visual differentiation between the rows not being skewed by highly expressed genes, the values of each sample were converted to z-scores with respect to the individual genes.

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