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This prospective, randomized clinical trial was approved by the Clinical Medical Research Ethics Committee of the First Affiliated Hospital of Anhui Medical University, Hefei, China (approval number: PJ2020-01-07) and was registered at Chinese Clinical trial Registry (http://www.chictr.org.cn/index.aspx, registration number: ChiCTR2000029932). This study was conducted in accordance with the declaration of Helsinki.

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