Basel Assessment of Adherence to Immunosuppressive Medications Scale

The BAASIS was a self-reported questionnaire developed by the Leuven Basel Adherence Research Group (Dobbels et al., 2010) and translated into Chinese in 2016. The previous study indicated that the BAASIS was reliable and valid to evaluate IM nonadherence in transplant recipients (Dobbels et al., 2010; De Bleser et al., 2011; Shemesh et al., 2017). We examined two dimensions of IM nonadherence in our questionnaire: implementation and discontinuation. Implementation was assessed by four questions (dose taking, drug holidays, timing deviation more than 2 h from the prescribed time, and dose reduction); overall IM nonadherence was defined as a “yes” to any of the five questions regarding to implementation or discontinuation in the last four weeks and data analysis was scored dichotomously. The BAASIS score was interpreted as acceptable in terms of reliability and validity, if the Cronbach’s α was greater than or equal to 0.78 (Dobbels et al., 2010; Shemesh et al., 2017).