Cue-Induced Reinstatement of Drug Seeking (Experiments 1–4)

LC Liangpei Chen
SH Shihao Huang
CY Chang Yang
FW Feilong Wu
QZ Qiuyao Zheng
HY He Yan
JY Jie Yan
YL Yixiao Luo
EG Ewa Galaj
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Twenty-four hours after the propranolol or saline treatment (i.p.), rats were subjected to the reinstatement test induced by drug cues. The test condition was identical to that of heroin self-administration training, with the exception that active nosepokes led to contingent presentations of the tone-light cue that had been previously paired with heroin and were not reinforced with heroin. The reinstatement test lasted 1 h.

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