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Resident–intruder paradigm

SP Shi-Xiao Peng
YW Yue-Ying Wang
MZ Min Zhang
YZ Yan-Yu Zang
DW Dan Wu
JP Jingwen Pei
YL Yansong Li
JD Jiapei Dai
XG Xiaoyun Guo
XL Xingguang Luo
NZ Ning Zhang
JY Jian-Jun Yang
CZ Chen Zhang
XG Xiang Gao
NL Na Liu
YS Yun Stone Shi
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An adult male WT mouse was used as an intruder. An intruder mouse was transferred into the residents’ cage (four males per cage), and attack episodes by the resident mice were recorded for 15 min. The intruder was typically attacked and defeated by the residents and showed submissive freezing behavior. Aggressive behaviors by the resident mice were scored; these behaviors were defined as biting, laterally attacking and displaying piloerection. The latency to the first attack bite, the frequency of bites and the duration of attack episodes were manually quantified. Data from four residents in the same cage were collectively analyzed as one unit.

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