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Statistical Analysis

LC Lin Chen
KZ Kunzi Zhang
JS Jian Sun
JT Jingtong Tang
JZ Jianping Zhou
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Statistical analyses were conducted using R version 3.6.3 (http://www.R-project.org). R package “Rtsne” was used to implement the t-SNE algorithm based on nonlinear dimensionality reduction. Moreover, the “xCell” R package was used to score tumor microenvironment stromal cells, while the “glmnet” R package was used for LASSO-Cox regression modeling. The datum was analyzed using appropriate standard statistical tests and the FDR method was used to adjust for several trials. Finally, we performed a multiple Cox regression analysis to adjust for covariates in order to determine independent survival risk factors.

Copyright and License information:  ©2021 Chen et al.
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