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2.2. MPTP induction to generate PD mice model
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MPTP–HCl procured from Sigma was diluted in 0.9% NaCl (1 mg/ml). It was administered intraperitoneally 4 times at a dose of 10 mg/kg every interval of one hour to finally achieve a complete dose of 40 mg/kg. Similarly, four intraperitonial injections of 0.9% NaCl was given to the mice in the control group.
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