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Statistical significance was determined by unpaired two-tailed Student's t test for comparison of two groups and one-way ANOVA with post hoc comparison for experiments consisting of three or more groups (GraphPad Prism; GraphPad Software, La Jolla, CA). P ≤ 0.05 was considered significant. All experiments were repeated independently at least three times.
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This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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