SEER Stat software (version 8.3.5) was used to download CCRCC clinical data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) database. The downloaded data included: patient ID, the year and age at the time of diagnosis, sex, race, histological type, survival time, tumor size, marital status, grade, SEER historic stage A, and cause of death.
CCRCC patients were selected according to the following criteria: (1) site record International Classification of Diseases for Oncology, Third Revision (ICD-O-3) was C649; (2) histological type was 8310/3; (3) the year at time of diagnosis was 1988–2014. (4) CCRCC was primary tumor. The exclusion criteria were listed as following: (1) patients without race and gender information; (2) patients whose tumor size, survival time and other clinical information we need in this study were unknown.
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