All women attending their routine second trimester ultrasound scan (19.0 23.6 weeks of gestation) will be invited to fill an eligibility questionnaire with a list of risk factors based on the criteria established by the RCOG [38]. The investigators involved in the recruitment will revise the inclusion/exclusion criteria and will address eligible patients about the purpose of the study and the voluntary nature of the participation. Women who agree to participate, after obtaining written informed consent, will be randomized and assigned a randomization code. Randomization will be performed using a web-based system which randomly assigns participants to one of the three different arms of intervention: (1) nutrition program based on MedDiet; (2) stress reduction program based on mindfulness techniques, MBSR; and (3) usual care without any intervention.
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