Patients

YL Ying Liu
XR Xiao-Ya Ren
YP Ya-Guang Peng
SC Shao-Ke Chen
XC Xin-Ran Cheng
MQ Miao Qin
XW Xiao-Ling Wang
YS Yan-Ning Song
LF Li-Jun Fan
CG Chun-Xiu Gong
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A total of 41 CHH patients aged between 12 and 18 years were enrolled in the current study from 2008 to 2019 in the Beijing Children's Hospital. The GnRH pump therapy has been used since 2008 and the hCG/hMG regimen started in 2016. We developed the treatment regimen by considering the average age of Chinese juvenile spermatorrhea (13–14 years)[15,16] as well as the expert consensus on the diagnosis and treatment of idiopathic hypogonadotropic hypogonadism.[5] Thus, administration of hCG/hMG began at an age older than 12 years and at a bone age (BA) of 12 years.

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