2.5.3. Apparent Permeability Calculation

NK Norraseth Kaeokhamloed
ER Emillie Roger
JB Jérôme Béjaud
NL Nolwenn Lautram
FM Florence Manero
RP Rodolphe Perrot
MB Marie Briet
CA Chadi Abbara
SL Samuel Legeay
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The apical-to-basolateral apparent permeability was calculated following the equation:

where dQ/dt is the appearance rate of a drug at the basolateral side (µg/s), A is the surface area of the Transwell® filter (1.12 cm2), and C0 is the initial concentration at the apical side (µg/mL) [21,37].

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