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Main outcomes: restricted mean survival time (RMST)

AM Akiko Matsumoto
CN Chiho Nakashima
SK Shinya Kimura
ES Eizaburo Sueoka
NA Naoko Aragane
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The RMST introduced by Royston and Parmar [27] of the progression-free survival (PFS) was used because a proportional hazard assumption has not been established between the rs671 groups for PFS (Figs. 1, S1). RSMT was estimated as the area under the survival curve between the time points (LIFETEST procedure in SAS 9.4, SAS Institute Inc., Cary, NC, USA).

Progression-free survival after the initiation of PD-1/PDL-1 inhibitor therapy. Kaplan–Meier plots were shown for patients with a thoracic malignancy. ICI, immune checkpoint inhibitor; Rs671(−), ALDH2*1/*1 (n = 56), rs671(+); ALDH2*1/*2 or ALDH2*2/*2 (n = 49). p, p value for Gahan–Breslow–Wilcoxon test

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