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4-((1H-Benzo[d][1,2,3]Triazol-1-yl)methyl)aniline (16)

RI Roberta Ibba
SP Sandra Piras
PC Paola Corona
FR Federico Riu
RL Roberta Loddo
ID Ilenia Delogu
GC Gabriella Collu
GS Giuseppina Sanna
PC Paola Caria
TD Tinuccia Dettori
AC Antonio Carta
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Compound 16 was obtained in 78% total yield; m.p. 151–153°C; TLC (petroleum ether/ethyl acetate 4/6); Rf = 0.47; 1H-NMR (200 MHz, DMSO-d 6) δ: 8.03 (1H, d, J = 8.4, H-4), 7.81 (1H, d, J = 8.4, H-7), 7.50 (1H, t, H-5), 7.41 (1H, t, H-6) 7.07 (2H, d, J = 8.2, H-3′,5′), 6.49 (2H, d, J = 8.2, H-2′,6′), 5.74 (2H, s, CH2), 5.15 (2H, s, NH2). 13C-NMR (DMSO-d 6) δ: 149.2 (C), 145.5 (C), 132.4 (C), 132.8 (C), 128.7 (2CH), 126.6 (2CH), 119.7 (CH), 114.6 (2CH), 110.3 (CH), 52.3 (CH2).

Copyright and License information:  ©2021 Ibba, Piras, Corona, Riu, Loddo, Delogu, Collu, Sanna, Caria, Dettori and Carta.
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