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Glycan nomenclature

AR Ana Lúcia Rebelo
FG Francesco Gubinelli
PR Pauline Roost
CJ Caroline Jan
EB Emmanuel Brouillet
NC Nadja Van Camp
RD Richard R. Drake
RS Radka Saldova
AP Abhay Pandit
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N-glycans share a common pentasaccharide with two core N-Acetylglucosamine (GlcNAc) and three mannose residues. F indicates a fucose residue, so if it is placed at the start of the abbreviation, it refers to core α(1,6)-fucose linked to the inner GlcNAc, whereas if it appears anywhere else, it indicates an outer arm α(1,3) or α(1,4)-fucose linked to antenna or galactose. Ax indicates the number (x) of antenna (GlcNAc) on the mannose residues belonging to the N-glycan core. Gx refers to the number (x) of β(1,4)-linked galactose on the antenna and Galx to the number (x) of α(1,3/4/6)-linked galactose on β(1,4)-linked galactose. Sx relates to the number (x) of α(2,3/6/8)-linked neuraminic acids (sialic acids) connected to galactose, while Sgx stands for the number (x) of glycolylneuraminic acids linked to galactose. Mx refers to the number (x) of mannose residues on the core GlcNAc (terminology used in oligomannose glycans). Lacs concerns the number (x) of poly-N-Acetyllactosamine repeats consisting of GlcNAc β(1,4)-linked to galactose.

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