Induction of Heart Failure in Rats

LA Lamiaa A. Ahmed
AM Ahmed F. Mohamed
EE Enas A. Abd El-Haleim
DE Dalia M. El-Tanbouly
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For induction of HF, rats were injected subcutaneously with ISO for two successive days at different doses (85 and 170 mg/kg, respectively) (Mohamed et al., 2015). Only animals exhibited electrocardiographic deviations (ST elevation) and high serum creatine kinase-MB 24 h after the 2nd ISO injection, were chosen to complete the study.

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