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Mutation assessor

AC Arunabh Choudhury
TM Taj Mohammad
NS Nikhil Samarth
AH Afzal Hussain
MR Md. Tabish Rehman
AI Asimul Islam
MA Mohamed F. Alajmi
SS Shailza Singh
MH Md. Imtaiyaz Hassan
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Mutation Assessor (http://mutationassessor.org/r3/) is a sequence-based tool that predicts the functional impact of an nsSNP on protein. The mutation assessor result is based on multiple sequence alignment and evolutionarily conserved residues51. The tool takes UniProt protein accession or NCBI Refseq protein ID as input for protein sequence and subsequently classifies the mutations as medium, low, or neutral for deleterious effects. The mutation assessor gives FI score for every non-synonymous mutation. If the FI score is more significant than 2.00, then the mutation is considered deleterious.

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