The same dosing solution as above was administered (0.5 mg/kg) to the rat (n = 3) by oral gavage with a 16-gauge feeding needle. Blood samples (~0.15 mL) were collected from the jugular vein at pre-dose, 5, 10, 15, 30 min 1, 2, 3, 4, 6, 8, 10, 12, 24, 28, 32 and 48 h post-dose.
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