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GO enrichment analysis and Pathway enrichment analysis

BH Baoquan Han
LW Lu Wang
SY Shuai Yu
WG Wei Ge
YL Yaqi Li
HJ Hui Jiang
WS Wei Shen
ZS Zhongyi Sun
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Gene Ontology (GO) analysis was performed using the website (http://metascape.org/) to reveal the unique biological significance based on differentially expressed genes. Using a combination of two websites (https://david.ncifcrf.gov/ and http://kobas.cbi.pku.edu.cn/kobas3), the Kyoto Encyclopedia of Genes and Genomes (KEGG) database was used to find important pathways. The “p-value < 0.05” and the “|log2fold change|≥2” were used as the cutoff criterion for GO and KEGG enrichment analysis.

Copyright and License information:  ©2021 Han et al.
This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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