If enough randomized controlled trials are included (>10), funnel plots or Egger's and Begg's tests will be used to assess potential publication bias. If there is no deviation in the included studies, the points on the funnel plot will be symmetrically dispersed around the estimated true values of each independent study effect point, showing an inverted symmetrical funnel shape. If there is asymmetric funnel plot, the more obvious the asymmetry, the greater the degree of bias, which may overestimate the therapeutic effect.
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