PrognoScan Database Analysis

The correlation between hepcidin expression and survival in lung cancer was also analyzed by the PrognoScan database (http://www.abren.net/PrognoScan/). The relationships between hepcidin expression and patient prognosis, such as OS and relapse-free survival (RFS), across a large collection of publicly available cancer microarray datasets can be investigated by using PrognoScan. To select the datasets to be included in this study, the screening parameters were set as follows: “Cancer Type” as lung cancer, “Subtype” as “adenocarcinoma” and “squamous cell carcinoma”. HR with 95% CIs was calculated. The threshold was adjusted to a Cox P-value <0.05.