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Unstimulated salivary flow rate measurement

MD Minh-Tung Do
HV Huong Vu
JL Jong-Koo Lee
SP Sang-Min Park
JS Joung-Sik Son
HK Hyun-Duck Kim
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Participants were advised not to eat or drink (except for water) about 8 h before the procedure in the morning in March (Spring) and September (Autumn). When coming to the test office, they were instructed to rinse their mouth with distilled water and take a rest for several minutes. The participants were instructed to swallow once before measurements began, then to keep on drooling for five minutes into a tube with previous weight measurement. They were also advised to minimize the movement of their mouth and not swallow any saliva during the procedure. The collected saliva was weighed and converted to volume (1:1 from grams to milliliters). The SFR (mL/min) was calculated by dividing the volume by time. Although previous studies [13, 24, 25] adopted hyposalivation (SFR <  0.1 mL/min), Dawes et al. [26] suggested low salivation (SFR < 0.3 mL/min). Since our data showed small numbers in cognitive impairment with hyposalivation (n = 31), we dichotomized SFR according to the suggestion of Dawes: normal SFR (≥ 0.3 mL/min) and low SFR (< 0.3 mL/min) [26].

Copyright and License information: The Author(s) ©2021
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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