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Animal model of acute lung injury (ALI) and treatment
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Thirty animals were randomly divided into three groups—blank, control and model groups—each containing ten mice. Lipopolysaccharide (LPS) (5 mg/kg) was administered intratracheally to induce ALI. NPs (10 mg/kg) were intravenously injected 1 day after LPS administration [29]. The chosen doses of these drugs were based on our previous studies and preliminary experiments.
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Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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