Structural Analysis

The structure of the IDPs in the condensate was quantified by their R_g values and was compared to the corresponding R_g values in the bulk. This comparison was made for a series of IDPs having different ϕ values and at different temperatures. In addition to the conformations of the IDP that comprise the condensate, the overall shape of the condensate may also depend on ϕ and T. To quantify the shape of the condensate, we estimated shape anisotropy by calculating the following parameter:

where d_x, d_y, and d_z measure the largest diameters of the largest cluster in the X, Y, and Z dimensions, respectively. Following this measure, a spherically shaped condensate has a shape anisotropy value of 3, while more elongated condensate shapes acquire values larger than 3.