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The skeleton density (Ds) was determined by an automatic specific surface area and pore size analyzer (3H-2000A, Beishide Instrument Technology Co., Ltd., Beijing, P.R. China). First, the empty tube volume of the sample (with the filling rod) was measured and recorded as V1. The sample weight (m) was accurately weighed by weight loss method, and the volume (V2) of tube containing the sample was measured by helium gas. The skeleton density was calculated using Equation (9). In order to eliminate the influence of moisture, the spray dried PNS powders were placed in a desiccator for 24 hours, before the skeletal density was measured.

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