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Gene Ontology (GO) was used to annotate biological processes, molecular functions, and cellular components of genes. Kyoto Encyclopedia of Genes and Genomes (KEGG) was used to annotate the gene pathways (Gene Ontology Consortium, 2015; Kanehisa et al., 2017). GO and KEGG analysis was performed using clusterProfiler package (Yu et al., 2012). P value <0.05 was considered as significant pathways enriched.
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