All experiments were performed in adult female (n = 8) KM mice between 6 and 8 weeks of age weighing between 18–25 g. Mice were housed on a 12 h/12 h day/night cycle. Mice were free to eat and drink. All procedures were approved by the Animal Ethics Committee (CEUA) of China Medical University (No. KT2018060). All surgeries were performed under anesthesia, and all efforts were made to minimize animal suffering.
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