Raw gene expression data were extracted from the Scanpy object as recommended in the “Using 10x data” section (inferCNV of the Trinity CTAT Project, https://github.com/broadinstitute/inferCNV). Normal reference cells were identified from annotated Leiden clusters as naïve T cells. Tumor cells were identified as malignant-like cells in Leiden clusters. The inferCNV analysis was performed following the tutorial (https://github.com/broadinstitute/inferCNV/wiki) with parameters including default settings.
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