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KF Karoline Freeman
RR Ronan Ryan
NP Nicholas Parsons
ST Sian Taylor-Phillips
BW Brian H. Willis
AC Aileen Clarke
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The annual incidence and 12-month period prevalence of IBD were determined for 2006–2016 considering all adult patients contributing data to IMRD in that period. Annual incidence was defined as the number of new cases of IBD during a 1 year period over the total time each patient was observed (person-time at risk). Period prevalence was defined as new and pre-existing IBD cases during a 12-month period over the number of patients in the IMRD database during the same time period. Confidence intervals for incidence rates were exact Poisson confidence limits. Confidence intervals for prevalence were calculated using the Wilson procedure for proportions without a correction for continuity. Incidence rates for male and female patients were compared using the two sample z test.

All analyses were undertaken in R version 3.6.1 (Vienna, Austria) [18]. The package “epitools” was used to calculate exact confidence intervals for incidence rates [19]. Graphs were drawn using the package “ggplot2” [20].

Copyright and License information: The Author(s) ©2021
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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