Some vendors may provide software which processes the raw chest motion data described in assessment attribute (I). The chest motion signals measured by the WRM sensors need to be conditioned before they can be used for calculating lung volume. This conditioning may include filtering noise and motion artifacts, and compensating for sensor drift. Some WRM dataloggers perform signal conditioning internally as the data is being collected, which allows them to calculate comprehensive metrics such as HR and RR. However, these dataloggers are typically “black boxes” and users may not have access to their proprietary algorithms. Other WRM dataloggers do not perform signal conditioning on the raw chest motion data; users would need to develop and apply their own preprocessing software.
After signal conditioning, the chest motion signals can be calibrated to known lung volume measured using a spirometer or other primary instrument. Some WRM manufacturers may provide software for calibrating conditioned chest motion data to lung volume data. If the calibration software is not provided, the user must develop their own algorithm or rely on third-party software. The correlation between the signal response from the sensor of the WRM to chest motion is a fundamentally important factor for calculating lung volume. There must be a one-to-one relationship between sensor response and chest motion for calibration to be successful. Currently, the only known commercially available software for this purpose is VivoSense (VivoSense Inc., Newport Coast, CA, USA). Academic research labs have developed software, such as TAP™ [30], to accomplish this calibration.
Some WRM manufacturers provide a software development kit (SDK) or an application programming interface (API) to interact with their WRMs. The SDK/API may provide access to either the raw chest motion data, the conditioned chest motion data, or both. Availability of an SDK/API would benefit those looking to develop their own signal conditioning, calibration, and/or inhalation topography analysis software.
Once the sensor signals have been conditioned and the chest motion waveform calibrated to a known volume, the lung volume waveform is obtained. The fidelity of that volume signal is limited by the sampling rate which was included in assessment attribute (I). Analysis software is required to determine the breathing cycle parameters for the inhalation topography parameters, including breath start time, inhalation flow rate, volume and duration, breath hold duration, exhalation flow rate, volume and duration, and pause between breaths. Currently, there is no known commercially available software for this purpose. Since inhalation topography requires identifying the start and end of each inhale and exhale, this process is not trivial, especially when dealing with long observations with many breathing cycles. A WRM that comes bundled with software that provides inhalation topography would directly suit our needs whereas a WRM that comes with no software would require significant engineering work to make it acceptable.
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