The COVID Symptom Study smartphone-based application (app), developed by Zoe Global Limited, and having almost four million users from the general population in UK, 280,000 from USA and around 175,000 from Sweden. Recruitment has been conducted through variegated advertisement campaigns (web-site, newspapers, etc.). Users self-report daily information about their overall health status, as well as their symptoms (from a pre-defined list, to standardise input)21,38. We included all pre-menopausal (if menopausal status was reported) women aged 18 to 44 years, who used the app between 24 March and 7 June 2020, and specified their pregnancy status at baseline (pregnant or not pregnant), including symptom profiles, outcomes on testing positive for SARS-CoV-2, and hospitalization (Supplementary Information S1).
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