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Patients were randomly assigned into two groups, liver biopsy performed after PA (n = 152) and SA (n = 171). A web-based randomization platform Urbaniak GC, Plous S (2021). Randomizer [online]. Website https://www.randomizer.org/ [accessed 01 July 2020]. was used, and randomization codes for either a PA or SA procedure were placed in sequentially numbered, sealed envelopes in the interventional radiology department. The radiologist who performed the biopsy procedure was aware of the approach, but the patients and the physician (CA) evaluating the pain were blinded to the method.

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