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The four English databases and four Chinese databases were searched from their inception to 31 August, 2020, including PubMed, Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure (CNKI, https://www.cnki.net/), WanFang Database (WanFang, http://new.wanfangdata.com.cn/), Chinese Scientific Journal Database (VIP, http://qikan.cqvip.com/), and Chinese Biomedical Database (Sinomed, http://www.sinomed.ac.cn/). The search strategy was as follows: ((“eczema” [MeSH] OR “eczema” [Title/Abstract]) OR (“dermatitis” [MeSH] OR “dermatitis” [Title/Abstract])) AND (“Runzao Zhiyang capsule” [Title/Abstract] OR “Runzaozhiyang capsule” [Title/Abstract] OR “Run Zao Zhi Yang capsule” [Title/Abstract]). In addition, the reference lists of relevant studies were also searched to identify other potentially eligible studies. The research was conducted by two independent authors (ML and BYZ), and any disagreements were resolved by the third author (LHZ).

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