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The statistical analysis of lifespans was performed with the IBM SPSS statistics 19 software package, and a Kaplan–Meier survival estimate was generated. Significance was evaluated using three independent statistical tests (Breslow, generalized Wilcoxon; log rank, Mantel–Cox; Tarone-Ware). In the figure legends, only the lowest p-values are indicated. A table with the exact values can be found in the Supplementary Tables 2, 3. To determine the significance of the other experiments, two-tailed Student’s t-test was used (∗∗∗: p < 0.001; ∗∗: p < 0.01; : p < 0.05).

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