Patients Follow-Up and Response Criteria

MF Marica Ferro
MF Milena Ferro
GM Gabriella Macchia
SC Savino Cilla
MB Milly Buwenge
AR Alessia Re
CR Carmela Romano
MB Mariangela Boccardi
VP Vincenzo Picardi
SC Silvia Cammelli
EC Eleonora Cucci
SM Samantha Mignogna
LL Liberato Di Lullo
VV Vincenzo Valentini
AM Alessio Giuseppe Morganti
FD Francesco Deodato
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Patients were evaluated three weeks after treatment completion and then every two months with clinical examination and blood tests. A contrast-enhanced multiparametric brain MRI was performed 45 days after RT completion and then every two months. Clinical response was evaluated based on the RECIST criteria in patients with macroscopic residual disease after surgery (24). In case of suspected pseudoprogression, a 6-[18F]-L-fluoro-L-3,4-dihydroxyphenylalanine-PET/CT was performed. In case of progressive disease in the brain, patients were considered for salvage treatment on a case-by-case basis (re-operation, second-line chemotherapy or re-irradiation).

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