Tumor cells secrete CXCL in order to recruit the immune cells such as neutrophils [55–57]. CXCLs and corresponding receptors (CXCR) such as CXCL5 and CXCR6 are important prognostic factors, alone or in a combination with the TANs, for shorter overall survival and cumulative risk of recurrence [3, 65, 66]. Thus the governing equation for CXCL8 is
where DC is the diffusion coefficient of CXCL, λC is the secretion rate of CXCL by tumor cells and μC is the decay rate of CXCL.
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