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Determination of percentage entrapment efficiency (%EE) and percentage loading capacity (LC%)

ME Mona Elhabak
SI Samar Ibrahim
SA Samar M. Abouelatta
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The percent drug entrapped was evaluated for all the prepared formulae. Briefly, 1 ml of the dialyzed samples was further sonicated (Elmasonic S 300, 220–240 V) with 10 ml warm ethanol for 15 min to ensure complete vesicles degradation (Tayel et al. 2015). LAA was determined using UV-vis spectrophotometer (JASCO, Tokyo, Japan) at 243 nm. The percent of drug entrapped, and drug loaded were calculated according to the following equations:

(Talebi et al. 2019).

The formula showing highest %EE and %LC was selected for further characterizations.

Copyright and License information:  ©2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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