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HapMap CEU panel

SC Seungho Cook
WC Wanson Choi
HL Hyunjoon Lim
YL Yang Luo
KK Kunhee Kim
XJ Xiaoming Jia
SR Soumya Raychaudhuri
BH Buhm Han
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HapMap CEU panel48 includes 4638 SNPs within the MHC region (chr6:26-34 Mb) genotyped using the Illumina GoldenGate platform and 4-digit classical HLA types for HLA-A, -B, -C, -DQA1, -DQB1, and -DRB1 from European individuals. HLA typing was carried out using PCR-SSOP-based protocols. For typing of class I, exon 2, intron 2, and exon 3 were examined. For typing of class II, exon 2 was examined. Genotype ambiguities were then resolved by direct sequencing of the whole PCR fragment. We downloaded the SNP2HLA-formatted data for 124 individuals from the SNP2HLA website5, which included 88 unrelated individuals.

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