COSMIC is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer (https://cancer.sanger.ac.uk/cosmic). It includes somatic mutation data from different research institutions and databases, and provides convenient browsing, retrieval and downloading functions. The main goal is to conduct in-depth study on cell samples commonly used in cancer research and analyze their mutation information [29]. We used the pie charts to depict the mutations in FBXO1 in BC and the distribution and substitutions on the coding strand.
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