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Kaplan–Meier plotter (KM plotter) database for survival analysis

YL Yaqian Liu
BP Bo Pan
WQ Weikun Qu
YC Yilong Cao
JL Jun Li
HZ Haidong Zhao
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We evaluated the prognostic significance of FBXO family members in KM plotter online database (http://kmplot.com/). The KM plotter was utilized to estimate the effect of 54 k genes (mRNA, miRNA, protein) on survival in 21 cancer types based on the gene arrays, RNA-sequence or next generation sequencing (for mutation data). Sources for the databases include GEO, EGA, and TCGA. The correlation between the target gene mRNA expression levels and disease-free survival rate (DFS), the overall survival (OS) rate, distance metastasis free survival (DMFS) and post progression survival (PPS) in BC groups were calculated by the Kaplan–Meier curve and log-rank test. The results were shown in the Kaplan–Meier survival plots. Hazard ratio (HR) and 95% confidence were calculated automatically by website tool. The values of each group are shown as the mean ± SD. P-value < 0.05 was regarded as statistically significant by using Log-rank test.

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