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Kaplan–Meier plotter (KM plotter) database for survival analysis

YL Yaqian Liu
BP Bo Pan
WQ Weikun Qu
YC Yilong Cao
JL Jun Li
HZ Haidong Zhao
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We evaluated the prognostic significance of FBXO family members in KM plotter online database (http://kmplot.com/). The KM plotter was utilized to estimate the effect of 54 k genes (mRNA, miRNA, protein) on survival in 21 cancer types based on the gene arrays, RNA-sequence or next generation sequencing (for mutation data). Sources for the databases include GEO, EGA, and TCGA. The correlation between the target gene mRNA expression levels and disease-free survival rate (DFS), the overall survival (OS) rate, distance metastasis free survival (DMFS) and post progression survival (PPS) in BC groups were calculated by the Kaplan–Meier curve and log-rank test. The results were shown in the Kaplan–Meier survival plots. Hazard ratio (HR) and 95% confidence were calculated automatically by website tool. The values of each group are shown as the mean ± SD. P-value < 0.05 was regarded as statistically significant by using Log-rank test.

Copyright and License information: The Author(s) ©2021
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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