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Quality of life (QoL) was rated by the patients at baseline and after 12 and 48 treatment weeks using the craniocervical dystonia questionnaire (CDQ-24), a 24-item disease-specific instrument based on the five subscales: stigma, emotional well-being, pain, activities of daily living, and social/family life (37). Patients with more than 20% improvement of CDQ24 were classified as responders, those with a worsening of more than 20% were classified as non-responders.

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