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Functional Enrichment Analysis and Survival Analysis

LZ Lili Zhang
WZ Wei Zhang
HL Hexin Li
XT Xiaokun Tang
SX Siyuan Xu
MW Meng Wu
LW Li Wan
FS Fei Su
YZ Yaqun Zhang
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The circRNA-related mRNA list was analyzed using the functional enrichment tool GOseq (Young et al., 2010). Compared with other tools, GOseq can alleviate selection bias more effectively. The pathways were drawn using ggplot2 (Wickham, 2016) in the R language. For survival analysis, TCGA PCa (PRAD) data were selected in UCSC Xena (Goldman et al., 2020) with progression free intervals to draw Kaplan-Meier plots of circRNA cognate genes. The expression level of the gene was used for survival analysis.

Copyright and License information:  ©2021 Zhang, Zhang, Li, Tang, Xu, Wu, Wan, Su and Zhang.
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